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Furthermore, we have observed that wolframin expression decreased in LP during the first trimester compared to the intense wolframin expression observed in the first trimester voluntary termination of gestation.
Given that inflammatory processes seem to activate parturition and are intertwined with early (or upstream), mid (or midstream) and late (or downstream) phases of the birth cascade, there are many research groups, including our group, focused on understanding how they trigger the termination of gestation.
Human placental samples were obtained with informed consent from first trimester voluntary termination of gestation (VTG, n = 15), first trimester loss of pregnancy (LP, n = 15), following birth from a vaginal delivery (VD, n = 15), from caesarean sections (CS, n = 15), and from caesarean sections of patients with diabetes mellitus (DMP, n = 15).
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First trimester decidua (7 12 wk of gestation) was collected from women undergoing elective first-trimester surgical termination of pregnancy with gestation confirmed by ultrasound scan.
Cases occurring in late miscarriages (20 23 weeks gestation), termination of pregnancy for fetal anomaly (TOPFA; any gestation), stillbirths (≥24 weeks gestation) and live births are notified to NorCAS.
It includes live births, stillbirths (from 24 weeks of gestation), spontaneous fetal loss (before 24 weeks of gestation), or termination of pregnancy because of fetal anomaly at any gestational age.
Criteria for exclusion after study enrolment are: spontaneous abortion prior to 20 weeks gestation; ectopic pregnancy; termination of pregnancy prior to 20 weeks gestation.
If the HELLP syndrome develops before 24 weeks' gestation, termination of pregnancy should be strongly considered [ 134].
Three umbilical cord samples obtained from Down syndrome fetuses and one from a healthy fetus after voluntary termination of pregnancy at 13 weeks of gestation were used for biochemical analysis.
The term abortion is defined as termination of pregnancy before 28 weeks of gestation.
Human testes were obtained after medical termination of pregnancy at 15 20 weeks of gestation.
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