Sentence examples for termination of dosing from inspiring English sources

The model successfully predicts liver tumor incidence for time points beyond termination of dosing with 2-acetylaminofluorene, but it is unsuccessful for bladder tumor incidence.

A discontinued dosing version of the Weibull model is proposed and is shown to predict successfully both liver and bladder tumor incidences for time points after termination of dosing.

Due to early termination of dosing, formal analysis of the primary end point was not feasible.

Using cows from both Latin squares, the flow of protozoal cells from the rumen was quantified by multiplying protozoal cell count in omasal fluid by the omasal fluid flow (using CoEDTA as a liquid flow marker) or was estimated by rumen pool size of cells multiplied by either the ruminal dilution rate of CoEDTA (after termination of CoEDTA dosing) or the passage rate of Yb-marked particles.

Due to early termination of OCR dosing, there was no formal primary end point analysis (change from baseline in modified total Sharp score (ΔmTSS) at week 104).

A two-day tail suspension test and a two-day forced swim test were carried out during four consecutive days after the termination of the dosing period, as described elsewhere [ 41, 43] (for scheme of study flow, see Figure 1(c)).

Subsequently, the mean tumour volumes of mice receiving short or continued ADI-PEG20 dosing were not significantly different at the termination of respective short dosing groups due to excessive tumour volume (1 IU: P=0.251; 2 IU: P=0.084).

Food intake reverted to normal levels within 10 days of dosing termination.

Factors that contributed to the lack of power are the small number of animals on test; a stop-exposure protocol for model rodent carcinogens; in a few cases, toxic doses that resulted in stoppage of dosing or termination of the experiment; and in a few cases, low doses administered to monkeys or early termination of the experiment even though the doses were not toxic.

Sodium nitroprusside infusion was started after the induction of anaesthesia and continued during and after termination of CPB with various doses according to the hemodynamic status until the 48th postoperative hour.

Unfortunately, it seems that termination of VF/PVT with such doses did not contribute to an increase in the immediate survival rate or final survival rate of our patients.