Sentence examples for termination complex from inspiring English sources
In the RF1 bound T. thermophilus termination complex, threonine 115 tightly packs against the universally conserved adenosine A-1493 [ 8].
CBC and Npl3p act synergistically to suppress transcription termination at weak polyadenylation sites by repressing the recruitment of the termination complex CF IA (cleavage factor IA) [ 33].
To prepare the sample for cryo-EM, the assembled termination complex was diluted in 1xHEPES-polymix buffer to a final concentration of 50 nM.
Thus, similar to yeast, a model was proposed in which formation of a PABP1 eRF3 eRF1 termination complex causes PABP1 to dissociate from the poly(A) tail.
Integrator recruitment to all three gene classes is DSIF-dependent, suggesting that Integrator functions as a termination complex at DSIF-dependent RNA Polymerase II pause sites.
CBC acts in synergy with Npl3p to repress the recruitment of the termination complex CF IA to weak polyadenylation sites [ 33]. miRNAs are endogenous transcripts that post-transcriptionally regulate gene expression in animals and plants.
This similarity to translation termination complexes suggested that Dom34 and Hbs1 function at elongation stalls to terminate translation, which has been demonstrated using reconstituted systems from both yeast and mammals (Shoemaker et al. 2010; Pisareva et al. 2011).
10.7554/eLife.00411.004 Figure 2. Termination complexes in association with RF1 alone and with both RF1 and apo-RF3.
The atomic details of termination complexes have not been fully elucidated in crystal structures and are sufficiently complex that constructing a credible atomic model for a termination intermediate would present significant challenges.
RRF (ribosomal recycling factor) and EF-G (elongation factor G) then bind to the 70S post-termination complex and, in a GTP-requiring reaction, dissociate the post-termination complex into the 50S subunit and the 30S/mRNA/deacylated tRNA complex.
Bacterial IF3 is a translation factor that acts at the interface between ribosomal recycling – splitting of the post-termination complex into subunits – and translation initiation.
