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From the fact that no terminating action was mentioned, we want to conclude that no terminating event occurred.
The first three axioms state the conditions under which a fluent can hold at a time t: either it holds right from the start or it is initiated at a time t1 before t without a terminating action occurring in between the two.
After a period of time, being a slow GTPase, Gα catalyzes the conversion of GTP back to GDP, allowing Gα(GDP) to again form a tight complex with Gβγ, thus terminating action (Gilman, 1987).
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DOI: http://dx.doi.org/10.7554/eLife.04366.002 Voltage-gated potassium (Kv) channels shape and terminate action potentials.
The type 2 diabetes MI/CV meta-analyses used four or five studies that included both the early terminated Action to Control Cardiovascular Risk in Diabetes (ACCORD; 3.5 years median) and the extension of the UK Prospective Diabetes Study (UKPDS; 15 years) (12– 12).
Parts of this action cancellation signal from the STN may also be relegated via arkypallidal pathways (orange pathways in Figure 1A) that relay inhibitory signals back up to the striatal neurons, offering a route for hyperdirect signals to terminate action plans within the striatum itself (Dodson et al., 2015).
Many therapies designed to reduce food intake and body weight act, in part, by blocking the dopamine transporter (DAT) — a protein responsible for clearing extracellular dopamine (DA) after release thereby terminating its action.
D3 converts the active hormone T3 to inactive metabolites thereby terminating TH action within cells.
KLK13 could mediate its role either by generating or activating breast cancer inhibitory factor(s) or by terminating the action of unfavourable factor(s).
AChE is responsible for terminating the action of the neurotransmitter acetylcholine (ACh) at pre- and postsynaptic nerve endings and neuromuscular junctions by hydrolyzing it.
The expression of GABA transporter (GAT) 1, which removes GABA from the synaptic cleft thereby terminating its' action (Hirunsatit et al. 2009), was present in most STN neurons (Augood et al. 1999).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com