For instance, they stacked the cards against themselves by purposefully picking a very hot year to start the analysis and a cool year to terminate the study (1998 and 2012, respectively).
Since patient recruitment was slower than expected, the sponsor decided to terminate the study at the interims analysis, and no further patients were enrolled.
Five patients prematurely terminated the study (one was lost to follow-up, two refused to continue and 2 for other reasons).
No subject terminated the study early or complained about side-effects apart from unpleasantness or mild pain upon nasal insufflation of CO2.
The participant was happy to continue after eating 36, but the decision was made to terminate the study for his own safety.
Spinardi suggests that STRAT-X was allowed to proceed so it could terminate the study for such a missile.
The DMC recommended that the trial be stopped; we thus decided to prematurely terminate the study in November 2005.
The DMC recommended that the trial be stopped, and we decided to terminate the study prematurely in August 2006.
Before participating the observers were informed about what participation would involve, and were told that they were free to terminate the study at any time.
Thus, it is possible that if we had terminated the study earlier, when growth rates were different, we may have found differences in tumor proliferation and apoptosis rates.
