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Secondary patency rate was defined as the proportion of patients with a patent bile duct at the end of follow-up after stricture resolution, including patients with stricture recurrence and successful repeat percutaneous biliary catheter treatment.Eleven patients terminated the protocol early, 6 as a result of treatment-related reasons in the orthotopic liver transplantation (OLT) group.
Five patients (50%) completed the protocol, while 5 (50%) terminated the protocol because of rapid disease progression or a severe adverse event; namely, interstitial pneumonia, related to gemcitabine treatment.
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No patients required hospitalisation and had to terminate the protocol treatment for this reason.
One patient (case 8 in Tables 1, 3 and 4) had a therapy-induced non-hematological adverse event, namely, hypoxia due to gemcitabine-induced interstitial pneumonia at 4 weeks from the last administration of DC vaccination, and this patient terminated the treatment protocol.
During the study, other psychotropic medications were forbidden; if needed, the patient was terminated from the protocol and referred to his or her PCP for alternative treatments.
However, lawyers said it would be difficult to terminate the Kyoto protocol because all parties have to formally agree by consensus to end it.
After 6 h of ventilation, the protocol was terminated, the animals euthanized, and necropsy performed.
If the protocol is terminated, the outcome can be considered a failure since prevalence rates quickly escalate.
Twelve patients received less allergen during the Week 13 allergen challenge than they received during the screening challenge, five in the active group and seven in the placebo group in each case, as mandated by the protocol, the Principal Investigator terminated the allergen challenge procedures early.
Termination: The protocol terminates in a finite number of steps.
Informally, a protocol that solves the consensus problem must fulfill the following properties:1 Agreement: If peers P i, P j are correct, then v i =v j Termination: The protocol terminates in a finite number of steps Validity: If all correct peers have the same input value (tilde v), then all correct peers decide on (tilde v).
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