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A third category has a so-called "nonsense mutation," which causes the cell to abruptly terminate production of the protein, making only a fragment.
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Our goal is to make the reporting of a potential shortage, or decisions to terminate production, mandatory so that the F.D.A. has more information and more time to avert access problems that may compromise patient care.
As such, the components of the prothrombinase complex are targets of multiple regulatory mechanisms to terminate the production of thrombin.
Sporulation of B. subtilis is a natural phenomenon which occurs in response to starvation, however the complete transformation of metabolically active cells to spores will eventually terminate the production of lipopeptides [ 19].
Microbial and cell cultures are composed of discrete organisms, each of which goes through a cell cycle that terminates in production of new cells.
After contact with an infectious dose of the virus, rapid viral replication in erythroid progenitor cells results in a high level viraemia which is terminated by the production of specific IgM antibody beginning around day 9.
In November, the government decided to stop the production of nuclear weapons and in February 1990, de Klerk issued written instructions to terminate the nuclear weapons program and dismantle all existing weapons.
The arm starts with the consumption of acetyl-CoA, which occurs in parallel in three cell compartments (the mitochondria, cytoplasm and peroxisome) and terminates with the production of squalene in the endoplasmic reticulum.
It is quite possible that the high copy number of Alu elements allows for pairing between regions of sequence identity of different Alu elements initiating the start of gene conversion before cellular control systems can terminate the process resulting in the production of small gene conversion tracts.
A De Beers unit also recently shelved a deal to acquire half of a Russian gem miner because of the financial crisis; another subsidiary just terminated a production agreement at a mine in South Africa.
Our recent study reported that miltefosine is able to prevent HIV-1 infected macrophages from activating the PI3K/Akt pathway, and specifically induces death of HIV-1 infected macrophages upon exposure to insults, ultimately terminating viral production [5].
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CEO of Professional Science Editing for Scientists @ prosciediting.com