Sentence examples for terminally affected from inspiring English sources

We should consider whether relations between the public and the British police – already strained by unusually oppressive behaviour and rudeness – may be terminally affected.

Matt Damon is the Winston Smith figure, a sad, decent, blue-collar ex-criminal who revolts against the system after becoming terminally affected by radiation sickness.

Interestingly the IGF1 signaling pathway was also over-represented when data from non-SN areas, unaffected or only terminally affected in PD, were considered.

When terminally affected with scrapie (a disease stage which is accompanied by fully developed clinical symptoms and indications that the animals become unable to take up sufficient quantities of drinking water), at pre-defined time points during the incubation period, or at 314 days after infection at the latest, the hamsters were sacrificed by CO2 asphyxiation.

Figures show representative data and show means±S.E.M. or S.D. In order to standardize a large series of experiments, we generated a 970 ml stock of 10% (w/v) RML prion-infected brain homogenate from terminally affected CD-1 mice and titrated this by intracerebral or intraperitoneal inoculation in CD-1 mice (Table 1).

Sub-cellular morphological studies of spleens from mice terminally-affected by scrapie and lymph nodes from clinically-affected sheep, have demonstrated that FDCs form abnormally convoluted labyrinthine structures, with abnormal accumulations of irregular, excess electron-dense deposits – containing putative immune complexes – between their dendrites [7], [8] [12].

Under conditions that efficiently degrade hamster and human PrPC, preservation of intact PrPSc was observed in brain homogenate from patients with vCJD or terminally clinically affected hamsters propagating the Sc237 prion strain.

We can therefore be confident that the PrP detected in terminally-affected mice is disease-associated PrPd irrespective of its conformation or aggregation state.

Brains from 400 terminally-affected CD-1 minfectedcted with the RML prion strain [42] were homogenized in Dulbecco's phosphate buffered saline lacking Ca2+ or Mg2+ ions (D-PBS) using tissue grinders to produce two pools of 10% (w/v) RML brain homogenate (designated I6200 and I8700).

In vitro studies have shown that such mechanical loading significantly affects terminally differentiated cells as well as lineage commitment in undifferentiated multipotent stem cells [3], [26] [44].

As the functional defect in CGD affects terminally differentiated myeloid cells, attempts were made to target gene expression to this cell population.