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Analysis of the amino terminal sequence by Edman degradation indicates that the sequence is unique.
The shorter rat brain-derived CaV1.2 isoform used for some experiments lacks this N terminal sequence.
This region is referred to as a "terminal sequence" hereafter.
This i4 variant is the COOH terminal sequence of all the isoformes [ 28].
Trailing terminal sequence regions not present in the MSA are included in the calculations.
Thus, the wild-type mtPAP demonstrated no preference for 3′ terminal sequence of the RNA substrate.
Similar(52)
Purified enzyme identified as a serine protease by N-terminal sequence was able to generate nACE.
One 135 kDa species had an NH2-terminal sequence of L33GRPSEEDEE.
Removal of this N-terminal sequence displayed mitochondrial localization, suggesting internal mitochondrial targeting signals.
The amino- and carboxyl-terminal sequence tails predicted a cellular localization (Fig. 1b).
Thus, in mammalian cAMP-dependent protein kinase (PKA), the C-terminal sequence participates in substrate binding.
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