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For example, the 3' EST NDL1_11_A06.b1_A029 in Additional file 1: Figure S3 C has the cDNA terminal pattern of 5TNS-4 + N + 3TNS-5 + N + 3TNS + V.
This has also allowed us to investigate the terminal pattern of disease and gain a better understanding of what challenges we are facing in treating DIPG.
Consequently, the 5′-end sequence contains cDNA sequence in the non-sense strand with a cDNA terminal pattern like N + 3TNS-1 + V + 3TSS-2, whereas the 3′-end sequence possesses cDNA sequence in the sense strand with a cDNA terminal pattern like 5TNS-2 + V + 5TSS-1 + N.
In the example shown in Additional file 1: Figure S2 F, the 5′-end sequence NXRV076_A06_F displays the cDNA terminal pattern of 5TSS + 3TNS-1 + V + 3TSS-2, and there is no cDNA insert detectable around EcoRI cut-off site.
As shown in Additional file 1: Figure S2 N, COLD1_26_G12.b1_A029 appears to represent this case, in which a 3′-EST displays the cDNA terminal pattern as 5TNS-2 + V + N.
This case is exemplified by NXCI_011_D03_F and NXCI_029_D07_F in Additional file 1: Figure S2 K and L, both of which have a terminal pattern of 5TSS-2 + V + 3TSS-2.
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Electron beam lithography was used to define anode and cathode terminal patterns.
The retinoblastoma epigenome mapped to the developmental stage when retinal progenitors switch from neurogenic to terminal patterns of cell division.
A simple mathematical model of this mechanism correctly predicts how the wild-type expression pattern of tll changes in mutants affecting the anterior, dorsoventral, and terminal patterning systems and some of their direct targets.
Following the sample preparation, four Au-coated spring probes were brought into contact with the current/voltage terminal patterns in a UHV-compatible cryostat.
Gro has many roles in Drosophila development, including roles in embryonic dorsoventral and terminal patterning, segmentation, sex determination, and wing patterning, while vertebrate Gro orthologs are required for such aspects of vertebrate development as cerebral cortex differentiation and cardiac development [5], [6].
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