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Terminal patches interdigitated with the induced dendritic bundles in BF, suggestive of a chemorepulsant effect on L2 dendrites.
First, there are two corticostriatal projection patterns from each prefrontal region: a focal projection field forming the well described, relatively confined, terminal patches (Graybiel & Penney, 1999), and a diffuse projection that consists of fibres that innervate a broad striatal region cutting across functional domains.
Only three positions were identified, occupied by polar residues on the first α-helix of the protein and replaceable by a hydrophobic residue, allowing an extended N-terminal patch that mediates bacterial agglutination.
Many members of the family also have a highly acidic carboxy-terminal patch, which is involved in transcriptional activation.
The patch M214 was located in the C-terminal while the patch centered at R100 was located in the N-terminal region of p24.
Motifs 1 and 2 form the N-terminal acidic and basic regions, while motifs 3, 4, and 5 form the C-terminal hydrophobic patch.
It is also worth noting that a previously reported small C-terminal basic patch that could function as a nuclear localization signal [ 17] is also conserved in all NASP family members studied here (data not shown).
The genome encodes many H2A and H2B variants and the repertoire of H2A.Z isoforms is expanded through alternative splicing, incrementally regulating the number of acetylatable lysine residues in the functionally important N-terminal "charge patch".
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