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Through the production of cAMP, activates cAMPdependent protein kinases (PKAs), triggering terminal differential and the production of spores.
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Terminal differentiation is associated with the acquisition of a heritable tissue-specific cell identity that depends on the differential expression of a predetermined set of genes.
15 Wnt family members can be differential regulators of the two steps of adipogenesis: an activator of preadipocyte commitment but a repressor for terminal differentiation.
The post-treatment prophylaxis was significantly better for DHA/PQP reflecting the differential terminal half lives of PQP and MQ (4 5 weeks for PQP and 14 days for MQ).
This can lead to N-terminal ragged ends due to differential amino-terminal processing because of the inability of the ste13p to process the large quantity of recombinant protein that is being produced [ 20, 23].
We also identified alternative N-terminal processing of H2AFY, as well as complex differential N-terminal processing of H2AFX.
We speculate that sequence divergence in the unstructured terminal segments results in differential recruitment of cofactors, perhaps defining the functional distinction between CTCF in somatic cells and CTCFL in the male germ line.
Mass spectrometry analysis and Edman sequencing of purified enzyme preparations revealed differential N-terminal post-translational processing of the various constructs expressed.
A specific focus is the late steps of fusion that are reportedly facilitated by (1) β-sheet-promoting β-branched amino acids (valine and isoleucine) that are enriched in the transmembrane domain of paramyxovirus F or (2) a post-translational modification of C-terminal cysteines with palmitate/stearate (differential S-acylation) that is highly conserved in Influenza virus HA.
In addition to identification of the novel PTMs described above, we revealed a differential N-terminal processing and modification pattern for the H2AFX variant.
Taken together, our observations suggest that ErbB4 del.3 transcripts are likely to generate a C-terminal truncated protein of differential function to wild-type ErbB4.
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