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Thus, we here establish that inactivating terminal components of the non-homologous end-joining (NHEJ) machinery or of the BRCA1-A complex specifically confer topotecan resistance to ATM-deficient cells.
Humoral cytotoxicity results from the assembly of terminal components of complement, called membrane attack complex (MAC), which lead to the formation of pores on pathogen membranes.
Sialic acids are mainly terminal components of glycans on glycoproteins and these sialated carbohydrates are involved in numerous cellular recognition process, such as pathogens adhesion (Kelm and Schauer, 1997; Schauer and Kamerling, 1995; Angata and Varki, 2002).
Another possibility is amino terminal components of intersectin-1L not present in our recombinant fragments could play a role in the regulation of exchange activity.
In several organ models of IRI, these terminal components of C3, C3b and C3d, are associated with tissue injury, and in transplanted organs with graft rejection [11], [12], [13].
Note that these TFs are not regulators but the terminal components of the pathways.
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Rubrerythrin in D. vulgaris functions as a terminal component of NADH peroxidase in the reduction of hydrogen peroxide to water [27], [29].
COX11 is a nuclear encoded mitochondrial protein and the terminal component of the mitochondrial respiratory chain.
Thus, during hypothermia, the concentration of activation products was reduced, including TCC, the terminal component of complement activation.
Cox7b encodes cytochrome C oxidase, subunit VIIb which is the terminal component of the mitochondrial respiratory chain and catalyzes the electron transfer from reduced cytochrome C to oxygen.
Small interfering RNA (siRNA -mediated knockdown siRNA -mediateded to assess the putative role of Doublesex, a terminal component of the sex determination pathway, in the regulation of sex-specific gene expression observed in the developing pupal brain.
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