I encountered the term "wild type" in my first semester as an instructor at MIT, in 7.02 (Introduction to Experimental Biology and Communication).
By now, I can list the procedures for an experiment on Pfu DNA polymerase almost by heart, but when I see the term "wild type" in a report, I still picture a single cell shimmying to music only it senses.
The term wild type virus corresponds to HIV-1 subtype C consensus throughout the manuscript.
We recognize that since BCR-ABL is a fusion protein that is not naturally occurring, the term "wild type" is technically incorrect.
For this reason, we have chosen to use the term wild type to describe the fusion protein that is observed in patients with CML.
The N-His6/D424A/C907S/L744C protein, termed the wild type (WT), was labeled with IAEDANS (Molecular Probes, Eugene, OR) as described previously.
Additionally, the two independent lines per 35S MYB transgene were nested factors [Transgene Genotype)] within the Genotype term (wild-type versus 35S MYB).
Examination of near-term wild-type and Mks1-mutant fetuses showed that both had multiciliated cells with motile cilia (see supplementary material Movie 3).
Note 1: Definition of "Wild-type" strains in the context of OptFlux simulations We use the term wild-type strain/organism in this study meaning strains that have a (approximately) known pre-definable steady-state flux objective function (e.g. biomass formation rate as in case of FBA).
To investigate whether this apoE4-induced decrease in spine density results from alterations in the formation or the loss of dendritic spines, the effects of neuron age and apoE isoform on the total number and subclasses of spines were examined in long-term wild-type neurons co-cultured with glia from APOE2-, APOE3- and APOE4-TR mice.
In the current study, the effects of apoE isoform and neuron age on the density and composition of NMDAR and AMPAR on dendritic spines were examined in long-term wild-type (wt) neurons co-cultured with glia from APOE-TR mice.
