Sentence examples similar to term pacing from inspiring English sources

To characterize the effect of short-term pacing-induced dyssynchrony on gap junction distribution in the mouse heart, we paced mice for 6 hours (3 4 half-lives of Cx43) [ 24- 26] and assessed Cx43 localization using immunofluorescence staining.

Complete AV conduction block is typically treated by implanting an electronic pacemaker device, although long-term pacing therapy in pediatric patients has significant complications.

Thus short-term pacing in Cx43+/− mice, but not in wild-types, was associated with significant changes in cardiac refractoriness and repolarization.

Clearly, the magnitude of altered Cx43 localization due to short-term pacing in and of itself is insufficient to result in significant arrhythmogenicity.

Thus, short-term pacing was associated with dyssynchrony during pacing and a slight decrement in ventricular function that normalized immediately after cessation of pacing.

To determine whether short-term pacing was associated with redistribution of Cx43 signal away from the intercalated disc, we performed colocalization analysis of Cx43 and cadherin immunosignal.

Thus, there was no effect of short-term pacing at rates just above sinus in wild type mice on electrocardiographic or electrophysiologic parameters.

To determine whether short-term pacing influenced synchrony of cardiac contraction, we examined mice prior to and during pacing using echocardiography.

In the setting of decreased Cx43 expression, short-term pacing results in significant prolongation of refractoriness, as well as changes in APD and Iss.

Cardiac memory has not been reported previously in the mouse model and in our study was not evident in wild-type mice after short-term pacing.

In this study, we have observed that short-term pacing at rates just over that of sinus rhythm eliminates the transmural gradient of Cx43 immunosignal area.