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Whereas the EF1α- and PGK promoters were shown to mediate stable long term expression of eGFP in hESCs, the CMV promoter only mediated transient expression [10].
Together these results suggest that CSPG can directly stimulate phosphorylation of EGFR and STAT3, as well as upregulate the long term expression of EGFR and Akt.
We have previously shown that lentiviral vectors can be used for the stable long term expression of erythropoietin (Epo) in rats [19].
The ACTB-, EF1α- and PGK promoters were found to be more efficient than CMV in driving long term expression of eGFP.
We previously demonstrated long term expression of Epo delivered by an intramuscular injection of a lentiviral vector in Fisher 344 rats [19].
Long term expression of bicistronic vectors was also compared to that of monocistronic vectors.
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Long-term expression of protein kinase C in adult mouse hearts improves postischemic recovery.
Dopaminergic mechanisms mediating the long-term expression of locomotor sensitization following pre-exposure to morphine or amphetamine.
Major advantages of lentiviral vectors are their ability to transduce nondividing cells and to confer long-term expression of transgenes.
Lentiviral vectors are able to transduce nondividing cells and maintain sustained long-term expression of transgenes.
However, there was no effect of conotoxin treatment on the long-term expression of amphetamine sensitization.
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