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To get a broader overview of the GO terms assigned to genes, the terms were traced back to the ancestral term at different levels in each of the gene ontology classes biological process, molecular function and cellular component.
In addition, its hierarchal structure allows a more specific disease term to be binned to a more general disease term at different levels which is especially useful for Disease Ontology enrichment analysis analogous to gene ontology enrichment analysis in experiments applying high throughput technologies.
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Tracking a word's arc from hip to lame is notoriously difficult, especially because different social groups grab hold of different terms at different times.
Tun-Wen Pai analyzed the GO terms at different depths.
The multiple-hypothesis correction [ 93] was adopted for discriminating the significant terms at different False Discovery Rates (FDR): 0.001, 0.01, 0.05, and 0.1.
Note that each g i can be annotated by many GO terms at different levels in GO's DAG structure (Direct Acyclic Graphs).
The original P values were adjusted using a modified Bonferroni correction method, which accounted for the nesting relationship among GO terms at different levels to avoid too conservative corrections.
Significant changes in baseline conditions, for example sudden reductions in blood volume or the occurrence of pneumothorax or haemothorax, may confound the interpretation of impedance changes in absolute terms at different time points [ 16].
However, we can point out some distinctions inherent in these terms: first, the terms appeared at different times.
How much of the total EA that leach from plastics made from these resins or other sources is consumed and absorbed by human subjects is another unknown as are short-term and long-term effects at different life stages (fetus, infant juvenile, adult, etc).
The MIMES requires that multiple ecological and human dynamics be specified, and that outputs may be understood through different temporal and spatial lenses to assess the effects of different actions in the short and long term and at different spatial scales.
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CEO of Professional Science Editing for Scientists @ prosciediting.com