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Second, we also present results using just Biomart GO term annotations for those species where gene products have been annotated.
To reduce the amount of data submitted, we allowed no more than 1,000 term annotations for each target.
The primary aim of MAA is to reproduce the MeSH term annotations created by curators.
This system aims to reproduce the MeSH term annotations on biomedical and chemical literature that would be created by indexers.
We use the term annotations in accord with Song and Agogino's (2004) definition, namely, a "type of support notation" metric, which includes "labels, lists, narratives, dimensions, and calculations" (p. 2).
However, the study also indicated that a subset of this dataset (with combined score ≥ 770) is more reliable with greater portion of it having correlated gene expression profiles and coherent informative Gene Ontology (GO) term annotations in both interaction partners.
764 probe sets with GO term annotations to cellular components demonstrated significant enrichment.
The GO term annotations for molecular function and biological processes were extracted from Ensembl for each gene [40].
To compare the features of these groups of probe sets, we categorized functions of these genes based on their gene ontology (GO) term annotations (Fig. 1).
Aligned sequences were mapped and assigned GO term annotations.
Term annotations were derived from controlled vocabularies (22, 23).
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