Both modules are enriched with the function of binding but tend to bind with different molecules.
Dynein has a net preference to move along a right-handed helical path, suggesting that the heads tend to bind to the closest tubulin binding site in the forward direction when taking sideways steps.
The unpaired probabilities, the probabilities of not forming pairs, are significantly higher than negative controls and the flanking sequence surrounding the binding site, indicating that SRSF1 proteins tend to bind on single-stranded RNA.
Most TFs tend to bind relatively few targets, with 57/155 unique proteins binding five or fewer promoters in at least one condition and 17 not significantly binding any promoters under any condition tested.
For example, TFs tend to bind in groups to form macro-molecular complexes, and the binding is thus stabilized by the presence of other TFs (Levine and Tjian, 2003).
In general, classical amino acid inhibitors such as 2(S -amino-6-boronohexanoic acid (ABH) tend to bind more weakly to S -amino-6-boronohexanoicaS -amino-6-boronohexanoichibitor binding modeS -amino-6-boronohexanoicite.
TFs tend to bind GC-rich regions in the genome, regardless of the distance and orientation34.
The ends of the peptide tend to bind more loosely in the capped form.
Finally, peptides tend to bind in the largest pockets available on the protein surface.
"He allows me to take as much thinking out of the game as I can, because I tend to bind myself up," Schmidt said.
After observing the changing methylation patterns, the MIT team identified many proteins that tend to bind to the DNA sites where those changes take place.
