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This work investigates such effects after temporary expression of vascular endothelial growth factor 165 (VEGF165), the most commonly used angiogenic protein for therapeutic purposes.
When the temporary expression of JARID1B is reverted, the melanoma will relapse.
To explain tumor-specific loss of LRP1b by mechanisms like homozygous deletions of exons, one would have to propose at least temporary expression of LRP1b during tumor development.
26, 27 In our experiments, continuous growth inhibition of xenografts with active AND gate genetic circuit demonstrated that after activation, the AND gate vectors could make persistent antitumor effects in vivo and might overcome the temporary expression from inducible promoter.
According to a recent study, during the period of de-differentiation there can be temporary expression of exogenous Oct4, which inhibits the transcription of Sox2, permitting subsequent mild activation of differentiation markers.
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By examining the temporary gene expression profiles, it is obvious that at a particular moment, the expression of a particular gene can be so low that the connection to this node (gene) is practically functionless.
Distinct from stable transgenic plants, plant RNA viruses provide a temporary, transient expression system.
The temporary, uniform expression of fss/tbx6 function restores dermomyotome in a wider domain of the paraxial mesoderm than it restores segmentation.
The VGlut1/VGlut2 overlap has previously been attributed to temporary co-expression of these proteins in the same synaptic terminals (Nakamura et al., 2007).
Do you think this period, what with the Occupy Wall Street concept, is just a temporary burst of expression that will go away because people will go back to watching American Idol or something?
They found that the altered genes could be grouped on the basis of their temporary pattern of expression.
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