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Finally, optogenetics presents the opportunity to achieve cell-type-specific control with a high temporal specification on a large enough scale to effectively repair network-level dysfunction.
Mourikis, P., Gopalakrishnan, S., Sambasivan, R. & Tajbakhsh, S. Cell-activityus Notch activity maintains the temporal specification potential of skeletal muscle stem cells.
Pletikos M, Sousa AAM, Sedmak S, Meyer KA, Zhu Y, Cheng F, Li M, Kawasawa YM, Sestan N (2014) Temporal specification and bilaterality of human neocortical topographic gene expression.
Thus, cortical RPs are transcriptionally primed to generate diverse types of neurons, and a Pum2/4E-T complex represses translation of some of these neuronal identity mRNAs to ensure appropriate temporal specification of daughter neurons.
Our study establishes Tgfβ as a regulator of temporal identity and potency of neural stem cells, and provides proof of concept that Tgfβ can be applied to modulate temporal specification of neurons in stem cell engineering.
Publications were assigned to 1 of 3 groups: (1) HHV-6B reactivation was analyzed as a time-dependent risk factor for subsequent aGVHD (n = 14), (2) aGVHD was analyzed as a time-dependent risk factor for subsequent HHV-6B reactivation (n = 1), and (3) analysis without temporal specification (n = 18).
Similar(46)
"Control Improvisation with Probabilistic Temporal Specifications".
"Debugging Temporal Specifications with Concept Analysis".
Control Improvisation for Probabilistic Temporal Specifications.
Mining Temporal Specifications for Error Detection.
This paper describes a novel method for debugging formal, temporal specifications.
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