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Most of the appropriate overrides were for prescriptions given for a temporal drop or fluctuation in the CrCL value below a specific drug's threshold (e.g., 50 mL/min for metformin and 30 mL/min for hydrochlorothiazide) or reference CrCL value, which was on the borderline.
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Furthermore, this continuous spawning of individuals may be induced in summer by temperatures above thermal stress (Múgica et al. 2015), and/or by temporal drops in salinity occurring at any time throughout the year (Fig. 4A, C).
Gain correction maps, available since CALDB v3.2.5, correct the spatial variations (for both HRC-I and HRC-S) as well as correct for the temporal gain drop (for the HRC-I).
Frame rate (temporal resolution) dropped significantly in the received images.
There were instances during interictal periods when the temporal correlations dropped significantly, but this was always a far smaller change than shown during the seizure event (Patient 1, maximal interictal shift = 1.3%, P = 0.02; Patient 2, maximal interictal shift = 0.8%, non-significant).
This is very important because we can rule out the possibility that the spatial pattern obtained in Fig. 4 is due to depth dependence of the estimated stress drop, temporal heterogeneity of earthquake occurrence, or size dependence of the stress drop.
Thus using a coding structure with p-pictures allows for temporal scalability by dropping the p-pictures without causing any prediction errors.
Another possibility is that the observed temporal change of stress drop was due to the temporal change of attenuation.
One explanation for the observed temporal change of stress drop is that fluid could have raised the pore pressure and decreased the shear strength of the fault, and this triggered earthquakes with a small stress drop.
where, for the sake of simplicity, we have dropped the temporal variable and have set the horizontal and vertical inter-sensor distances equal to d.
The pairwise c-indexes for these models (Table 4) show that pairwise discrimination among the three malignant events clearly dropped on temporal and external validation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com