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In order to identify histone demethylase inhibitor templates, we applied this assay for high-throughput screening of a diverse compound library, comprising the Molecular Libraries Small Molecule Repository (MLSMR) and additional collections, against the 2OG-dependent histone demethylase JMJD2E (KDM4E).
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For the online search of literature, we defined a detailed search template, which we applied to appropriate databases.
As an initial validation of the PET-template based image processing protocol, we applied it in a small cohort of patients.
To identify genes specifically altered in the late adolescent period, we applied a template matching procedure.
Furthermore, we applied the template 'Gene(s) + Flanking region → Specific overlapping features' with 'histone_binding_site' as the SO term name to query the 1 kb upstream region of our 116 genes to find all histone binding sites.
First, we applied the AAL template to define the nodes for each subject's network.
Therefore, we applied a hollow-template-guided approach to further localize the inner mass within the chamber of the cavity-occupied TRiC average.
We applied FLASH with a template sequence length of 198-bp and a read length of 108-bp.
In this section, we outline how we apply a template-based approach for modeling a sequence of repetitive dance figures performed on music.
Finally, we apply the conventional template matching algorithm using the template to the gallery image sequences, and then calculate a head-based matching score.
In [5], the time-dependent parametric and harmonic templates are applied to NMF when the pitch of a note varies.
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