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Over exploitation of medicinal plants with limited bioactive principles has provided templates to design synthetic drugs in AD e.g. rivastigmine, phenserine, eptastigmine based on chemical structure of physostigmine of Physostigma venenosum Balf.
The utilization of metal-organic frameworks (MOFs) as precursors or templates to design synthesize nanostructured metal oxides has attracted intense interest for their great potential applications in gas separation/storage, drug delivery, catalysis device, gas sensors, etc.
In the case of the artificial HBV-targeting pri-miRs, natural miR-122 and miR-31 sequences were used as templates to design the exogenous RNAi activators.
In stage 4, the subsequences were selected from the qualified sequences, and they were used as templates to design the qualified siRNAs.
These regions (all inside a CpG island) were used as templates to design qPCR primers using the PrimerQuest online tool (Integrated DNA Technologies).
SNPs and SSRs can also be used as templates to design primers that amplify specific genomic DNA in diverse populations [ 28].
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This regulated autonomous deposition of the fibers will build patterned 3D-structure with unique properties on the surface of the templates, leading to a novel type of nanotechnology using biological systems with biomolecular nano-templates to design 3D-structures.
Compound 13 may become a useful template to design new NAAA inhibitors.
Moreover, MOF may be suitable template to design the define shape with pores of different metal oxide.
Parotid secretory protein (PSP) (SPLUNC2), a potential host-defense protein related to bactericidal/permeability-increasing protein (BPI), was used as a template to design antibacterial peptides.
To prove the validity of our model we used it as a template to design a novel derivative of the known DNA methyltransferase inhibitor 5-azacytidine.
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