Sentence examples for templates structures and from inspiring English sources

Use templates, structures and specially dimensions and measures used for defining draft of specification.

By and large, the quality of comparative modeling depends on two factors: the availability of reliable template structures and the extent of structural similarity between target and template, which in turn is determined by the extent of the similarity between their sequences (Chothia and Lesk, 1986).

Finally, comparative models were built for the parts of the sequence aligned by the FR methods to the template structures and the sequence conservation was analyzed in the structural context to detect potential active site residues (see below).

Focusing on the influence of conformational details in the template structures, we based our study on 8 experimentally determined template structures and generated 120 designs from each.

(iii) If a homology model exists, we then check for sequence identity (S.I). between the query and template structures and the completeness of the homologous structure.

The results of the threading on top five template structures and their secondary structure composition in each model are shown in Table 1.

The transmembrane helices are relatively well conserved in conformation, with the intracellular and extracellular loops being much more variable (Figure 1)–this is also evident in the MSA of the five template structures (Figure 2) and the MSA of the five template structures and 14 target GPCRs (Figure S1, supporting information).

Again VORESCORE is used to rescore the model structures against the native template structures and rank all the models.

It ranks template structures and selects the most likely candidates and estimates the reliability of the obtained lowest energy model.

Results files contain the superposed template structures, and the alignment between each subunit file and template file are generated inside the HHpred program.

Briefly, the target sequences were aligned with the template structures, and coordinates from the templates were transferred to the targets TRR1 and KRE2.