Sentence examples for templates for structure from inspiring English sources

These tools are sensitive enough to detect even very remote homologous templates for structure modeling.

Thus, the structural studies led to a deeper understanding of kinase regulation and provided new templates for structure based design of selective inhibitors.

The conservation of protein structures among homologs allows these structures, in most cases, to represent the general fold of the query protein and to be suitable templates for structure modeling.

Since hRNase7 shares high primary sequence identity to hRNase6 and hRNase8, 58%and75%5%, respectively, its structure was used as a template for structure simulation of hRNase6 and hRNase8 which have no resolved 3D structures yet.

Three-dimensional (3D) homology model of Leishmania donovani geranylgeranyltransferase-II (LdGGTase-II) was generated by comparative modeling using MODELLER 9v8 [ 56] with crystal structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase and isoprenoid from Rattus norvegicus (PDB ID-1LTX) was selected as a template for structure modeling.

The structures of SiCYS-N and SiCYS-C appeared alike using those structures as templates for structural prediction.

The ability to execute such ideas has made Second Story a useful template for structuring, managing and staffing a 21st-century publishing, production and communications company.

Both binding sites may serve as a template for structure-based design of novel complement therapeutics.

Our structures, along with mutagenesis and kinetic studies, provide a molecular basis for understanding pathogenic mutations and catalysis, as well as a template for structure-based drug design.

Further, we have confirmed the validity of the HTP structure as a template for structure-based drug design by predicting binding affinities for TPI and other known HTP inhibitors using in silico docking techniques.

In this study, we applied ligand docking and molecular dynamics refinement to a P2Y14R homology model to qualitatively explain structure activity relationships of previously published synthetic nucleotide analogues and to probe the quality of P2Y14R homology modeling as a template for structure-based design.