Sentence examples for template yielded a from inspiring English sources
The design based on the IKK-β active site, and a privileged structure template yielded a novel IKK-β inhibitor scaffold with significant selectivity over IKK-α and CHK2, as assessed by an in vitro kinase assay.
The direct approach based on the PET template yielded a maximal difference between the measurements in MNI or OIS of 2.2% in the caudate nucleus (mean -0.8, SD 1.4) and 3.7% in the putamen (mean -1.2, SD 1.4) (Figure 5).
The results of this approach indicate that Ntl129A is a null mutant, as none of the primer pairs tested using Ntl129A/Ntl129A DNA as template yielded a PCR fragment corresponding to that obtained from the wild-type control (Table 2).
As shown in Figure 2A, negative control with the wild type SCUT27 genomic DNA as template yielded a 2.2 kb fragment.
The best CoMFA model using atom-fit alignment approach with the bound conformation of compound 21 as the template yielded the steric parameter as a major contributor (nearly 70%) to the observed variations in biological activity.
Subsequent loading of the siRNA into the RNAi silencing complex, followed by action of RNA-dependent RNA polymerase (RdRP) on target mRNA template, yields a population of secondary siRNAs that are able to interfere with gene expression through transcriptional repression, translational block, or mRNA cleavage [ 2, 4, 11- 13].
Configuring SINA to use a column profile as alignment template yielded lower accuracy (Fig. 3).
In comparison, pha-1 (ts) coselection using a similar sense nhr-23 :: 2×FLAG repair template yielded seven knock-ins from 27 screened pha-1 (ts) rescued F1's.
A negative control, with water in place of the RNA template, yielded no bands during the RT-PCR or standard PCR steps.
An injection current of 20 mA in the LEDs with and without the PSS-ANP template yielded forward biases of 3.7 and 3.75 V, respectively.
However, all transformants lost a part of cadA during 16 h cultivation on liquid LB medium as PCR analysis with these cultures as template yielded fragments of only 0.3 kB (data not shown).
