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Using the structure of the bacterial transporter homolog leucine transporter as a template, we developed a structural model of SERT.
In this work, by merging the masking and scaffolding modalities of the MCC template, we developed a unique single-step process for creating binary and ternary patterns on a surface over large areas (>1 cm) with excellent structural programmability.
By combining the masking with the scaffolding modalities of the MCC template, we developed a unique single-step process for creating binary and ternary patterns on a surface over large areas (>1 cm).
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The neutral beam (NB) etching and ferritin bio-template we developed have recently brought about a great breakthrough in that we successfully fabricated two-dimensional (2D) array Si nanodisks (Si-NDs) with sub-10 nm, high density (>1011 cm-2), and quasi-hexagonal crystallization [16 20].
By using our previously developed ALK inhibitor 6 and the clinical Hsp90 inhibitors AUY922 or AT13387 as the templates, we developed several series of resorcinol tethered 2,4-diaminopyrimidines as ALK/Hsp90 dual inhibitors bearing various linkers at different linking sites.
Building on our earlier finding that PCR fragments with 35-base homology are efficient repair templates, we developed an entirely cloning-free protocol for the generation of seamless HDR edits without selection.
To address these shortcomings, by combining double network polymerization and sphere-templating fabrication techniques, we developed a tough, intelligent scaffold based on poly acrylic acid) and poly N-isopropyl acrylamide) with a controllable, uniform, and interconnected poly N-isopropyl.
To minimize duplicate efforts to visualize the results from JSON exporters, we developed template web application projects to visualize JSON files generated by Cytoscape.
Figure 1 illustrates the workflow of the template-based modeling that we developed for the structure prediction of H3.
To generate templates for IVT mRNA, we developed the pcDNA3-A(124) vector plasmid and BIRC5-inserted vector plasmids from artificial custom genes, according to a protocol described previously [ 16, 17].
Finally, we developed standardized template forms for forward and back translations and expert panel discussions.
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