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Combretastatin A-4 (CA-4) is a well-studied and attractive molecular template to develop new antimitotics.
The protease inhibitors have shown different levels of inhibition and may thus provide template to develop selective and potent drugs against these devastating arboviruses.
Collective efforts toward further optimization of this novel tricyclic template to develop better porcupine inhibitors will be subsequently undertaken and reported in due course.
We have used a near-infrared fluorescent protein iRFP engineered from a bacterial phytochrome as the template to develop an in vivo split fluorescence complementation probe.
Appendix 1 outlines a draft CML computational chemistrydictionary for molecular orbitals, and shows a formatted example that can beused as a template to develop a molecular orbital convention in the future.
Furthermore, molecular modeling studies indicate that a central pyrimidine ring serves as a suitable template to develop dual inhibitors of cholinesterase and AChE-induced Aβ aggregation thereby targeting multiple pathological routes in AD.
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Then, we found that they were using one of the more traditional templates to develop the US, such as presented by Cohn (2004).
Although different venomous animals often use distinct scaffolds as templates to develop their own 'pharmaceutical factory', the ICK fold appears to be conserved across several evolutionarily distant venomous animal lineages.
Benzoxazolone and benzothiazolone were used as template blocks to develop two series of dimers as anti-inflammatory and analgesic agents based on the concept of bivalent ligands.
We report a facile soft-template approach to develop polyaniline (PANI) nanostructures in various morphologies (nanotube, nanorod, nanosphere and nanosheet) by triggering the amount of N-cetyl-N,N,N-trimethyl trimethylammonium bromide (CTAB) surfactant.
When you're looking for a template to follow to develop your own homegrown talent, Manchester United's 'Class of 92' isn't a bad place to start.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com