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Here we used this crystal structure as a template to assess the likely positioning of the ectoine and 2-oxoglutarate ligands within the active site by structural comparison, molecular dynamics simulations, and site-directed mutagenesis.
Marco et al. [64] used a model based on the yeast eEF1A template to assess the ability of a potent inhibitor of protein synthesis (didemnin B) to bind human eEF1A1.
While our framework offers a template to assess preparedness to address the challenges of breast cancer, additional research is needed to validate the taxonomy.
In a previous study we developed a template to assess whether a clinician could use the treatment described in a randomized trial with a patient tomorrow [ 21].
We used regulatory interactions identified in E. coli as a template to assess the variability of regulatory interactions of each individual regulon across all the organisms included in the database.
We selected the first five papers in RefWorksTM and coded them separately using the template to assess whether there was good agreement between coders and if the template failed to capture sections of the papers.
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Luo et al. [10] proposed an algorithm that first uses square concentric templates to assess the candidate red-eye regions and then employs an Adaboost classifier coupled with a set of adhoc selected Haar-like features for final detection.
The physiotherapists used computerised templates to assess patients and record findings.
However, these inferences must be tested with many additional combinations of sgRNAs, loci, and repair templates to assess their generality.
While SSH libraries were constructed using pooled mRNA samples, QPCR was conducted using individual RNA templates to assess biological variability.
Development of practical, standardised templates to assess causes of stillbirth is underway, which, if adopted internationally, will help to more accurately measure the burden of intrapartum versus antepartum stillbirths and their associated causes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com