Sentence examples for template structures to from inspiring English sources

We found a significant difference among the eight template structures to realize the above three criteria despite their high structural similarity.

The model is first built by transferring the Cα coordinates of the template structures to the aligned residues in the query sequence.

This is done by directly transferring the Cα coordinates of the template structures to the aligned residues in the query sequence.

1J96[14] was chosen as a template for homology modeling due to the presence of the testosterone substrate in the crystal structure; this being the most similar substrate in any of the potential template structures to DHT.

Second, we developed DFGmodel, a method based on homology modeling that utilizes a diverse set of DFG-out template structures to generate kinase models in the inactive, DFG-out conformation.

The full catalytic domain has slightly higher RMSD (1.11 Å) despite the identical sequence, suggesting that the N-lobe can adopt a range of positions relative to the C-lobe in DFG-out crystal structures, supporting our approach to use multiple template structures to represent the rigid movement of the N/C-lobes.

We used the template structure to define eight agent-oriented pattern templates.

The X-ray structure of IgFLNa17-GPIbα complex (pdb-code: 2BP3) [14] was used as a template structure to model the IgFLNa23 into peptide-binding conformation.

This technique requires a homologous template structure to be identified and the sequence of the modeled protein (a target) to be correctly aligned to the template.

For each domain, 50 models were generated with MODELLER using the above corresponding best fit as a template structure to refine the stereochemistry.

An essential advantage of TASSER over traditional comparative modeling methods, which often deteriorate the quality of template models, is its ability to drive the template structures closer to the native than the input templates.