Although this study was initially guided by the theoretical concept of salutogenesis, the analysis remained entirely datadriven and Antonovsky's theory was not used as a template, but solely helped to define the research question and to structure the themes in the applied interview guide.
The most important feature of information-driven theoretical approach is that it designs aptamer templates based solely on the structural information about biomolecular targets.
An information-driven theoretical approach, EFBA, has been proposed for the computational design of aptamer templates based solely on structural information of the biomolecular targets [ 72].
We have proposed an information-driven theoretical approach which is an entropy fragment-based approach (EFBA), for the computational design of aptamer templates based solely on structural information of the biomolecular targets [ 11].
Collectively, there is no simple explanation for how all the known missense mutations in αS result in PD and their divergent effects on in vitro aggregate formation suggest that conformational templating cannot solely account for disease progression.
Each of ~15 ng tracerA1 and tracerA2 were hybridized with ~1,500 ng driver for 20 h at 60°C. 2 μl of the hybridization result was used as template to amplify solely tracer fragments using the adapter primers A1 (5'-TGTAGCGTGAAGACGACAGAA-3') and A2 (5'-TGTAGCGTGAAGACCTGTCTT-3').
In this initial study, however, we greatly simplify the system by assuming that replicases do not discriminate between inter-species and intra-species replication, so that the replication rate constants, k SP, k SM, k DP and k DM, are dependent solely on templates.
As before, it is assumed that k SP = k SM, that k DP + k DM is constant, and that replicases do not discriminate templates (i.e. k SP, k SM, k DP and k DM are solely dependent on templates).
However, control experiments revealed that cross-linking was not determined solely by supramolecular templating.
