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The distal template is positioned in the usual position for a supracondylar osteotomy.
The template is positioned within an acyclic chain whose length and bond orders are systematically varied, and the conformational space of each structure that results (core plus chain) is explored to determine whether it is able to link together two or more strongly interacting functional groups or pharmacophores located within a protein binding site.
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Acrylic radiographic templates were positioned to allow the realignment of different CT scans.
In contrast, structures of pol β with active site mismatches indicate that the incorrect templating base is positioned upstream of the coding template base pocket creating a pseudoabasic site (i.e., coding potential of the templating pocket is lost).
The duplex segment of primer-template DNA is positioned in the central chamber of the clamp loader where it is stabilized by basic residues and amino-terminal helix dipoles lining the interior surface of the clamp loader spiral.
As found in a recent crystal structure of the ternary complex of Pol η with the correct nucleotide and DNA substrate containing a cisplatin-induced lesion (47), the enzyme is able to preorient the incoming nucleotide and two metal ions in the active conformation even if the templating nucleotide is positioned outside the active site.
When DNAP is in the post-translocated state, the N + 1 templating base (blue) is positioned in the polymerase active site ready to base pair with the incoming dNTP.
The templates ensure the artwork is positioned correctly for various workflows.
In order to facilitate this work we propose a simple template to be positioned on the radiographs, which will make it possible to rapidly evaluate the alignment of the metatarsals and the corrections necessary for re-establishing correct architecture of the forefoot.
Templates, primer-ends and nucleotides are positioned at the active site, the 3' hydroxyl of the primer-end attacks the α-phosphate of the incoming dNTP, pyrophosphate (PPi) is released and the primer-end translocates to allow for the addition of the next nucleotide [1].
The incoming nucleotide paired with the 5′-neighbor template, while the primer 3′-hydroxyl was positioned to facilitate extension.
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CEO of Professional Science Editing for Scientists @ prosciediting.com