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The obtained results would help to better design a remediation technology to be applied to the sites contaminated with mixed wastes, and the statistical methodologies used in this study appear to be very efficient and could serve as a template for optimization.
The hIL-25 cDNA (GenBank accession number BC069565) was used as template for optimization to generate a set of ten overlapping oligonucleotides (as showed in Table 1), of which G+C content was adjusted to meet codon preference.
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The results offer an improved template for further optimization of BoNTA endopeptidase inhibitors and demonstrate that the CaDA approach is useful for both design and optimization of zinc protease inhibitors.
The results offer an improved template for further optimization of BoNTA endopeptidase inhibitors and demonstrate the effectiveness of the cationic dummy atom approach in the design and optimization of zinc protease inhibitors.
This study is a significant extension of our previous report on the dimeric ADK-containing IN inhibitors, providing a new promising template for further lead optimization.
The obtained results showed that the most potent compounds could be useful as a template for future design, optimization, and investigation to produce more active analogues.
A 103 base synthetic oligonucleotide template was used as an artificial amplicon for optimization of primer design for rhPCR.
We then give two templates for dynamic programming along a semi-nice tree-decomposition, one for optimization problems over vertex subsets and another for optimization problems over edge subsets.
Given the set of control points P, determine the displacement of every selected control point p i ∈ P by means of template-matching technique using entropy of histogram of differences as similarity measure and hill-climbing algorithm for optimization.
Pseudo-Boolean optimization was used for optimization.
No strict constraints are applied for optimization.
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