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"At the moment it's very template driven," said Manu Gupta, co-founder of the National Alliance for Disaster Risk Reduction in India.
However, in contrast to proteins and nucleic acids, biosynthesis of oligosaccharides in mammals is not template driven [ 8].
8 For example, when a clinician is following a template driven diabetes check-up, serious non-diabetes related symptoms that the patient mentions in passing may not by documented or acted on.
Since glycan synthesis is not a template driven process (as compared to peptides and proteins which can leverage the genome), target libraries need to be experimentally determined or predicted in silico.
In the context of highly managed and time-limited consultations the normalisation of depression in people with LTCs underscored tensions between template driven approaches to case-finding, and strategies that were less regimented and more patient centred.
Similar(55)
Fusion PCR thus allows rapid, cost-effective generation of sgRNA templates driven by the U6 promoter.
Third, the de novo appearance of genomic insertions supports our original contention that cryptic sequence templates drive some of these changes.
This signal, which radiates from the chromatin template, is driven primarily by phosphorylation events, mainly on serine and threonine residues.
The mobile clamp together with the α-ribbon and proximal NPs could mediate the RNA template translocation driven by the polymerase motor.
Conversion of PrPC in vivo is presumed to occur following direct interaction with the pathogenic protein, which acts as a template to drive the conformational change to PrPSc.
Finally, the C-terminal domain (CTD) of the v-SNARE (VAMP2 or synaptobrevin) rapidly zippers along the pre-structured t-SNARE template to drive fast membrane fusion.
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