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The current technique has overcome the limitations of previously described threshold and template comparison techniques in detection of complex evoked synaptic signals with variable amplitudes and superimposed events.
Our algorithm manages to detect multiple or pairs of events that are separated in time by less than the length of the templates, which previous template comparison techniques would not be able to (e.g., see Clements and Bekk, 1997).
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An important novel feature of our technique is utilization of a bank of matched filters for the detection stage, which offers several advantages over previous techniques of template comparison.
This major issue of single template comparison has been avoided in our new technique, as an array of filters based upon identified EPSCs from experimental data in the training stage provides a range of templates with variable shapes and durations that potentially match a variety of EPSCs found in experimental recordings.
Gao and Skolnick [ 4] predict DNA-binding using structural template comparison and statistical potential.
Thematic analysis and constant comparison techniques were used for analysis.
As the published methods with detection algorithms based upon amplitude thresholding and fixed or scaled template comparisons are of limited utility for detection of signals with variable amplitudes and superimposed events that have complex waveforms, previous techniques are not applicable for detection of evoked synaptic events in photostimulation and other similar experimental situations.
Synthesis occurs generally through electrochemical methods, synthetic chemical routes, nanoimprint lithography, template assisted techniques, and chemical vapor deposition technique [39].
All the systems submitted allowed INV and OOV query detection, because they were based on template matching techniques.
The composite nanotubes were prepared using spin coating and template immersion techniques.
This is especially important when there are no structural homologs existing in the database or the template identification techniques cannot find good templates (Zhang, 2008b).
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