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We will develop and pilot a data extraction form using the Cochrane Consumers and Communication Review Group Data Extraction Template (available at: http://cccrg.cochrane.org/author-resources).
For DBM, we registered every brain non-linearly to the MNI152-2009c templavailablelatle at http://www.bic.mni.mcgill.ca/ServicesAtlases/ICBM152NLin2009) and computed the deformation applied at each voxel using the procedure explained in Aubert-Broche et al. (2013).
Alignment of corresponding anatomical structures in images (prior to segmentation) from different participants was achieved by linear registration to a standard brain template comprising images from 152 participants placed into the stereotaxic coordinate space (MNI template available at http://www.bic.mni.mcgill.ca/software/).
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The template, available to any region that is interested, consists of a straight bargain.
The databases containing precompiled models are based on the best template structures available at the time the model was computed and usually focus their efforts on a limited number of target proteins for efficiency reasons.
Whole brain templates are available at http://brainatlas.brain.riken.jp/jm/modules/xoonips/listitem.php?index_id=9.
All the tool templates are available at http://bit.ly/mkYm0V and are free to use.
Of the possible templates available in the PDB at the time of preparation of this paper, D3 shared the greatest number of aligned prolines (five in total) with both hOX1 and hOX2 receptors, including the important proline in position 4.59.
ICBM152 MNI template is freely available at http://www.bic.mni.mcgill.ca/ServicesAtlases/ICBM152NLin2009.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com