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We conclude that all three products meet the target profile described earlier, and would be appropriate for short-term ambient temperature shipping from field clinics to diagnostic laboratories.
The effects of two common blood sampling methods (serum vs. plasma) and two widely-used serum handling methods (on the clot with ambient temperature shipping, "traditional", vs. centrifuged with cold chain shipping, "protocol") on protein and autoantibody concentrations were examined.
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The samples were milled identically using a "flow-through" mill (Satake Rice Whitener MCM-250) and were stored for approximately 1 month at room temperature before shipping to IRRI.
Saliva (~5 ml) was collected in Oragene collection devices (DNA-Genotek, Ontario, Canada), stored at room temperature, and shipped at ambient temperature through the US mail.
The milled rice was stored for 1 week at room temperature and shipped to IRRI.
In contrast, the collected blood spots can be dried in room temperature and shipped without refrigeration.
Samples stored at ambient temperature were shipped by courier to the central laboratory on the same day as collection, while frozen samples were shipped every 3 weeks.
Human papillomavirus samples were stored at ambient temperature and shipped to the Department of Pathology of the Vrije University Medical Centre, Amsterdam, The Netherlands for HPV DNA testing.
PAP smears, PreservCyt vials and histological material were stored at room temperature and shipped to Norway and Sweden for preparation and interpretation by well-experienced cytotechnicians and pathologists.
The tubes were stored for up to 48 h at room temperature then shipped overnight at 4 °C to Bio-Rad where they were processed upon receipt.
The card with the taped hair sample was placed into a pre-labeled envelope and stored at room temperature until shipped to the Channing Trace Metals Laboratory, Brigham and Women's Hospital, Harvard T.H. Chan School of Public Health for analysis in Boston, Massachusetts.
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