Although batch cultures are well-suited to study low temperature adaptation dynamics, they are poorly adapted to study prolonged exposure to low temperature.
Molecular mechanisms of temperature adaptation.
Low, P. S., Bada, J. L. & Somero, G. N. Temperature adaptation of enzymes: roles of the free energy, the enthalpy and the entropy of activation.
Gatti-Lafranconi, P. et al. Evolution of stability in a cold-active enzyme elicits specificity relaxation and highlights substrate-related effects on temperature adaptation.
Our results provide a framework for further research on epigenetic temperature adaptation of invasive species to better explain and predict their rapid range expansions.
This chapter outlines the evolutionary protein design methods that are used to help uncover the molecular basis for temperature adaptation in enzymes.
Here, the structural stabilizing role of residue Lys209 was verified, and semi-rational protein design was applied to further improve capacity of higher temperature adaptation.
Protein engineering is a powerful technology to tailor various enzymatic properties including catalytic efficiency, substrate specificity, temperature adaptation and even achieve new catalytic functions.
What is NOT discussed: there are physiological limits to temperature adaptation in all plants, and those limits are being approached for some cereal crops in the African Sahel.
Although many mesophilic or psychrophilic strains of Shewanella and γ-proteobacteria were sequenced for their genomes, the genomic evolution pathways for temperature adaptation were poorly understood.
We suggest that whereas UCP1 in iWAT plays an important role in protection against obesity, UCP1 in iBAT is essential for temperature adaptation.
