Sentence examples for telemetry model from inspiring English sources

The purpose of this study was to determine the sensitivity of a canine telemetry model with intravenous ECG lead placement: the negative ECG lead (solid tip) inserted into the jugular vein and the positive lead sutured to the diaphragm.

The presented telemetry model provides an excellent method to evaluate PTL drug candidates.

In the dog telemetry model, the onset of reflex tachycardia (in response to hypotension caused by vascular calcium channel blockade) also confounds the interpretation of QT interval changes (Fridericia's formula) seen following verapamil administration (Toyoshima et al., 2005).

The overall findings from this literature analysis are in complete agreement with a recent cross-company data-sharing initiative, which demonstrated that the conscious dog telemetry model was valuable for predicting QT outcomes in a phase 1 clinical study (Ewart et al., 2014; n = 113 small molecules in dataset).

Dogs are commonly used in cardiovascular drug safety assessment, and implanted telemetry models include subcutaneous or epicardial electrocardiogram (ECG) electrode placements.

The aim of these studies was to evaluate the correlations between pharmacologically-induced ECG changes in the anesthetized cardiovascular guinea pig (CVGP) with ECG changes in conscious non-rodent telemetry models, human clinical studies and effects on key cardiac ion channels.

The fish were anaesthetized with benzocaine, weighed and measured and each supplied with a small radio transmitter [Advanced Telemetry Systems; model F1520 (length: 19 mm, depth: 8 mm, weight: 1.3 g)] surgically implanted into the stomach cavity (procedure as described by Jepsen and Berg [23]).

We anesthetized animals and implanted telemetry transmitters (Model F20-EET, DSI, St. Paul, MN, USA) for simultaneous recording of two biopotentials (EEG and EMG).

In this paper, the proposed telemetry system models the dynamic response of the helicopter to pilot inputs under artificially generated wind conditions and then uses neural network based models to estimate the air wake distribution.

Device programming was performed using transcutaneous telemetry (CareLink® Model 2090 Programmer with software Model SW026, Medtronic Inc., Minneapolis, MN) and mid-winter data retrieval utilized wireless telemetry from a relay station (Medtronic MyCareLink® Patient Monitor Model 24950, Medtronic Inc., Minneapolis, MN).

While standard dog telemetry is the model of choice to investigate preclinical CV risk and make a quantitative translation to human, it is largely set up to investigate acute, functional, tightly PK-driven effects such as ECG effects.