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'Conclusion': The HTA provides a clear conclusion regarding the medical effectiveness or cost-effectiveness of the health technology (technologies) under assessment.
'Limited conclusion': Authors on an HTA formulate a general suggestion regarding the medical effectiveness/cost-effectiveness of the health technology (technologies) under assessment, but the conclusion is limited because of the limitations of the reviewed evidence.
The majority of these (51 reports) provide only a general opinion on the medical effectiveness or cost-effectiveness of the health technology (technologies) under assessment (CAT II V); thus, further research is likely to have an important effect and may change the conclusion.
The analysis of the legal implications reported that the two technologies under assessment could be considered super-imposable in their measurement considering the indication of use for all the surgical procedures and for all the categories of patients, and the presence of authorisations of use. Figure 3 reported the evaluators' perception concerning the equity dimension.
Safety The safety of patients (in terms of evaluation of adverse events, mortality or morbidity related to the technologies under assessment) and of healthcare professionals, as well as the environmental impact related to the use of the different technologies, was investigated using a 5-level Likert scale, ranging from a minimum of 1 (worst impact) to a maximum of 5 (best impact).
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The rest of the models calculate health outcomes specific to the character of the disease or the technology under assessment.
For example, the EUnetHTA programme "attempt[s] to define and standardise elements of an HTA" by dividing relevant information on the technology under assessment "into standardised pieces, each of which describing one or more aspects of the technology that is likely to be useful when considering the adoption or rejection of the technology".
The submission comprised a description of the technology under assessment and the clinical context of its use, followed by a review of the available clinical literature relating to the effectiveness of the intervention and comparator technologies; and an economic submission, with a review of relevant economic evidence, a de novo cost analysis, and a spreadsheet model.
HTR Healthh technology reassessment; HTA Healthh technology assessment; HTAi: Health technology assessment international; INAHTA: International network of agencies for health technology assessment.
This dimension required a description of the technology and the pathology under assessment and, in addition, the definition of the real and potential catchment area of reference for the procedures.
Normally, the assessments of comparability made under reference pricing are not as detailed as those made under technology assessment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com