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If their profits are to keep rising at the current clip of 10% a year in a market that is growing at only half that rate, drug firms must find more innovative medicines.This is a formidable task, though probably not impossible for firms that can exploit new technologies for discovering drugs.
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Data mining (DM) is a promising technology for discovering knowledge hidden in large data.
ESTs represent a relatively quick and inexpensive technology for discovering new genes, for obtaining data on their expression and regulation, and for the construction of genome maps [ 13].
Growing interest and burgeoning technology for discovering genetic mechanisms that influence disease processes have ushered in a flood of genetic association studies over the last decade, yet little heritability in highly studied complex traits has been explained by genetic variation.
Among such tools, genome-wide transcriptomic profiling seems to be a powerful yet straightforward, affordable and easily validated molecular biology technology for discovering new diagnostic biomarkers and drug targets [ 4, 5].
Here, we provide a brief overview of the various technologies that are useful for discovering and/or genotyping rare variants.
The advent of next-generation sequencing technologies opens a new era for discovering genome diversity and genetic mapping.
The developments of mouse models for NCLs as well as the advancements of microarray technologies have opened the way for discovering affected molecular pathways on a genome-wide scale.
Frederick Hausheer, BioNumerik's founder and chief executive, expects his firm's modelling technology to cut the time for discovering new drugs by a third to a half.In a similar vein, Aventis has used several models of cells and disease mechanisms to discover a number of new compounds.
He is the man responsible for discovering the technology behind airships, as well as for the creation of manufacted, or artificial, nethicite.
Salivary transcriptional profiling technology has been successfully applied for discovering detection biomarkers of resectable pancreatic cancer [34].
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CEO of Professional Science Editing for Scientists @ prosciediting.com