Other types of SBF are also available (Müller and Müller 2006; Hu et al. 2006; Wen et al. 2009; Gemelli et al. 2010) and the interested readers are referred to a leading opinion co-authored by the SBF inventor (Kokubo and Takadama 2006), where the entire history and the preparation techniques of various SBF formulations are well described.
The microspheres were prepared by an oil-in-water emulsion/solvent evaporation technique and the effect of formulation and processing parameters (polymer concentration in the organic solvent, volumes ratio of the phases, rate of the organic solvent evaporation) on microspheres characteristics (size, loading, morphology, release) was investigated.
In spite of the differences in surgical techniques, PRP formulation, size of the lesions, retear rate have been recalculated by combining the available data from studies in order to determine the role of PRP in improving the rotator cuff healing after surgical repair.
In conclusion, QbD paradigm not only offered a robust FHMG technique to formulate controlled release formulations of hydrophilic drugs but also provided a time and cost saving advantage to pharmaceutical industry.
In this work, in an attempt to improve the delivery efficiency, the INS-loaded polymer lipid hybrid nanoparticles (INS-PLGA-lipid-PEG NPs) were designed and constructed through a double-emulsion solvent evaporation technique, followed by formulation of the spherical micro-particles using a spray freeze dryer (SFD).
However, pragmatic solutions utilize some understanding of the degradation and matching techniques in their formulation.
It was demonstrated that the use of mechanistic models in combination with selected analytical techniques allows rapid formulation of microparticles for respiratory drug delivery using batch sizes of less than 80 mg.
Application of the classical optimization technique aided the formulation of an optimal strategy for minimization of power losses on transmission lines.
The basic idea behind these regularization techniques is the formulation of nonlocal constitutive equations by introducing some effects of characteristic lengths representing the materials microstructure.
Significant increases in the absorption of the UV spectrum were detected in seven of the eight formulations studied, demonstrating the potential of this measurement technique in the evaluation of formulations developed as potential topical ocular sunscreens.
This reduction technique enables the formulation of a plate impactor structural system of minimum size (1 term per vibration mode for composite plates – 2 terms for sandwich plates) and reduces computational cost, thus facilitating applicability for real-time impact and vibration control.
