Once in vivo, the accurate and reproducible assessment of TKR design mechanics is exceedingly difficult, with the secondary variables of the patient and the surgical technique hindering research.
However, inherent drawbacks of the 2-D gel separation technique hinder its application for in-depth comparative analysis, as mentioned above.
Despite the similarities between the two techniques, the different failure modes in the two reconstructions suggest that the jail technique may hinder the upper lag screws from cutting through the cancellous bone during loading.
Cloning was the traditional approach for uncovering allelic variants in allopolyploids in these nuclear ortholog allopolyploid studies, but this technique is hindered by the formation of chimeric sequences combining the sequences of different alleles [ 47], high labor, and high cost [ 48].
However, lack of long-term stable synchronization techniques has hindered the realization of this pervasive clocking idea.
These and similar techniques are hindered in their acceptance since these specialized sequences may not be routinely obtained.
Unfortunately, these techniques are hindered by limited specificity.
Otherwise, the application of these ready-available MRI techniques is hindered by the presence of different confounding factors (i.e., T1 relaxation effects, T2* decay, spectral complexity of fat, noise bias, B0 inhomogeneity, and eddy currents), that require proper correction [ 10, 12, 17– 17].
Yet, the application of this technique is often hindered by the crystallization liability of the drug.
