This study aimed to describe the rate and timing of HHD therapy discontinuation, or technique failure, and identify contributing factors.
Despite substantial advances in peritoneal dialysis (PD) as a renal replacement modality, PD-related infection remains an important cause of morbidity, technique failure, and mortality.
However, all estimates need to include the total costs, including infrastructure, patient training, and maintenance; patient attrition by death, transplantation, technique failure; and the necessity of in-center dialysis.
Methods: A randomized controlled trial was undertaken at 2 metropolitan teaching hospitals comparing the effects of straight versus coiled PD catheters on time to catheter malposition (primary outcome), catheter-associated infection, technique failure, and all-cause mortality.
Secretions were properly managed, which is essential for preventing technique failure and the need for endotracheal intubation.
Technique failure and peritonitis rates were in general within acceptable limits and independent of the method of assistance (done by either nurses or family members) [ 44, 45].
Canadian patients living more than 50 km from their treating nephrologist were less likely to suffer technique failure and transfer to haemodialysis (HD), but suffered increased mortality [ 6].
Patients were encoded as either MC or other when small numbers of cases were present (individual causes of PD technique failure and cause of death).
Peritoneal dialysis-related peritonitis (PDRP), the major complication of CAPD, is the leading cause of severe morbidity, technique failure and mortality in PD patients [ 8, 9].
Together with the induction of inflammatory processes, this can lead to loss of peritoneal membrane function, technique failure, and premature discontinuation of PD therapy [ 2].
