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It is technically difficult to identify all heterozygous SNPs in the genome; if we lower the threshold, the number of false-positive SNPs increases drastically.
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Of course, mass spectrometry would be more definitive, but ppGpp is technically very difficult to identify by mass spectrometry.
However, where loss of a tumour suppressor gene function is a known determinant of the disease, it is difficult to identify a direct therapeutic target as it is often technically complex to efficiently recapitulate tumour suppressor function.
Other relics were more difficult to identify.
"It was difficult to identify them".
They said that it remained technically difficult to weed out duplications without better access to election records, and that their internal auditing identified many of the fraudulent registrations, which they flagged for election officials to review.
It is a complicated process, and technically difficult to study, Kang says.
Some time series applications require data which are either expensive or technically difficult to obtain.
The card would be sophisticated but not technically difficult to produce.
It is technically difficult to track consumers as they hop from phone to computer to tablet and back again.
However, because it is technically difficult to perform ESD of the colon, ESD is not a commonly used technique.
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