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Science educators have advocated using stories from the history of science to convey the numerous cultural, personal, and technical variables that come to bear on the development of an idea (Irwin, 2000; Tao, 2003; Clough, 2011).
Although there are many technical variables that could impact on the reproducibility of an IHC method, such as processing and embedding tissue and selection of section thickness, [ 27] the major source of error is recognised as that which is introduced by the reader [ 28, 29].
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Technical decisions change output variables that are monitored through a graphical multi-criteria analysis of environmental and social sustainability attributes.
The first five principle components were significantly associated with variables that included technical covariates (batch and array), blood cell type composition, but not cancer status (see "Methods" section).
Thus, we have found the jackstraw to also be useful in the context of dealing with latent variables that reflect technical effects of no biological relevance.
Besides the potential technical biases discussed above, other critical variables that could have deep implications in the accurate interpretation of circulating miRNA biomarker studies are related to the intrinsic interindividual variability and to the influence of disease-independent factors.
The data may also be corrupted by experimental uncertainties and sometimes do not contain all information regarding variables that cannot be measured for technical reasons.
This means that overlapping and competing agendas exist, decisions are not discrete and technical, and that facts and values are intertwined – all variables that characterize the process of decision making.
As "suitable," we may consider that it properly deals with variables that present complex relations such as stakeholders' preferences, technical constraints, limited resources, and subjective business aspects.
Data for all 248 participants were modeled by using predictor variables that had been determined by bivariate analysis to be associated with RVFV seropositivity (Technical Appendix 2).
And there are innumerable variables that can affect that".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com