mFluidX– mFluidX has created a diagnostic chip the size of a pack of gum that replaces bulky and technical laboratory instrumentation for DNA / RNA analysis.
The main reasons for this are technical: surgical instrumentation for the S.T.A.R. prosthesis is more difficult to use and the lack of trial implants caused many ankle surgeons to switch to the AES (Table 4).
Authors thank Anna University Trichy, Chennai for technical help and instrumentation usage.
Bifurcation percutaneous coronary intervention (PCI) is still a difficult call for the interventionist despite advancements in the instrumentation, technical skill and the imaging modalities.
The authors want to kindly thank Dr. Thomas E. Wales for technical assistance with instrumentation and hydrogen exchange mass spectrometry.
Many of these approaches focused on exploration at the gene expression level, and frequently require special instrumentation, technical expertise and can be time consuming.
Moreover, as explained above, the expected traces of life would probably be very subtle and, due to the technical limitations of instrumentation, difficult to detect in situ.
Analytical reproducibility is a requirement for the implementation of all diagnostic tests, but it is especially critical for decentralized tests given the challenges of maintaining reproducibility across pathologists, technical operators, and instrumentation.
We thank Dr. Zhi-Gang Xiong (Dow Neurobiology laboratory, Legacy Holladay Park Research Center, Portland, Oregon) for helpful discussions and technical assistance with instrumentation and Mr. Jeff Gadette (Oregon Episcopal School (OES), Portland, Oregon) for his advice on statistics.
In this Review, we aim to cover the theoretical background and technical advances in instrumentation, software, and experimental methods underlying the major developments in 3D structure determination of macromolecular assemblies by EM and to review the current state of the art in the field.
