It could be because of technical differences in sensitivity and specificity of the different assays, the amount and quality of RNA available, or biological differences of the target molecules.
In the case of microarray studies, the differences in technologies and cutoffs used for the identification of differentially expressed genes, the different genes represented on each array and technical differences in RNA and hybridization, analysis protocols and references used often hinder the identification of common regulated genes [ 33].
This illustrates that there is greater similarity between the expression profiles of the two cell lines than there is between technical differences in the experiment (i.e. the two different microarray formats).
Although technical differences in experimental design undoubtedly play a part in creating these differing hit lists, a significant factor are recent advances in dsRNA library design.
Technical differences in the networks of the major United States carriers mean that cellphone makers must customize each phone's design for individual carriers.
There are significant technical differences in these imaging systems including spectral band response, pixel dimensions, swath width, and radiometric resolution which produce differences in observation data sets.
Future academic curriculum and training techniques could be developed to reflect these potential technical differences in search behavior, diagnostic technique, and surgical selection strategy.
In addition to technical differences in microarray and RNAseq methods, predicting bacterial vs. non-bacterial rather than distinguishing viral, bacterial and mixed viral/bacterial infections may have reduced the prominence of interferon related genes identified in the current study.
Though the four devices in common use have technical differences in design and in how they are implanted, doctors say the choice of device matters far less than the experience of the surgeon.
The measure will go to Mr. Clinton for his signature after the House and Senate work out technical differences in their bills over whether the changes should apply in the month that people turn 65 or in the year that they turn 65.
