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Technical deviation was defined as a presumed technical error as proposed by Schneider et al. [14].
In the presence of various confounders, such as the technical deviation between runs and biological variability, one of the challenges in RNA-Seq data analysis is to extract real biological responses from substantial amounts of transcriptomic expression data.
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In almost all 26 patients, at least one observer identified one of the respective technical deviations.
No correlation between the DASH score and the number of technical deviations was seen (p = 0.64).
Our secondary hypothesis is that interobserver agreement on the total number of technical deviations is poor.
We would have expected higher than fair agreement on the total number of technical deviations per TBW construct given that some potential technical deviations were not subject to interpretation, such as single wire knot and prominent wire knot(s).
There was no correlation between technical deviations of the TBW surgical technique and long-term objective and subjective outcomes [6].
We also hypothesized that there is no correlation between technical deviations of the TBW surgical technique and long-term objective and subjective clinical outcome.
Due to low number of implant loosening or breakage (one patient, 4%) we lack power to correlate any potential technical deviations to loss of fixation.
The lack of correlation between technical deviations and outcomes suggest that most of the Schneider criteria [14] are irrelevant from the patient's perspective.
There was also no correlation between the elbow arthritis score according to Broberg and Morrey and the number of technical deviations (p = 0.99) [1].
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